Issue 10, 2013
From the journal:

Journal of Materials Chemistry B

Responsive poly (γ-glutamic acid) fibres for biomedical applications

Sangwon Chung,a   Cristina Gentilini,a   Anthony Callanan,a   Martin Hedegaard,a   Søren Hassingb  and  Molly M. Stevens*a  

* Corresponding authors

a Departments of Materials and Bioengineering and the Institute of Biomedical Engineering, Imperial College London, UK
E-mail: m.stevens@imperial.ac.uk
Tel: +44 (0)20 7584 6804

b Institute of Technology and Innovation, University of Southern Denmark, Campusvej 55, DK-5230 Odense M, Denmark
E-mail: sh@iti.sdu.dk
Fax: +45 65507384
Tel: +45 65507414

Abstract

A novel responsive system using a protein-based biopolymer was designed to undergo structural, geometric, and chemical changes upon temperature change or solvent interaction. Poly(γ-glutamic acid) (γ-PGA) is an attractive candidate for various biomedical applications as it is naturally produced, biocompatible and enzymatically degradable. The responsive material was fabricated using an electrospun modified γ-PGA to create a sub-micron fibrous mat. By modulating the environment responsive behaviour in a controlled manner, exciting applications such as wound dressing, compression materials and self-tightening knots are envisaged.

Graphical abstract: Responsive poly (γ-glutamic acid) fibres for biomedical applications

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Article information

DOI
https://doi.org/10.1039/C3TB00515A
Article type
Communication
Submitted
10 Dec 2012
Accepted
18 Jan 2013
First published
30 Jan 2013

J. Mater. Chem. B, 2013,1, 1397-1401

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Responsive poly (γ-glutamic acid) fibres for biomedical applications

S. Chung, C. Gentilini, A. Callanan, M. Hedegaard, S. Hassing and M. M. Stevens, J. Mater. Chem. B, 2013, 1, 1397 DOI: 10.1039/C3TB00515A

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