Synthesis of novel functionalized cispentacins through C–C oxidative cleavage of diendo-norbornene β-amino acid†
Abstract
Difunctionalized cispentacin derivatives with two new stereogenic centres have been synthesized from a diendo-norbornene β-amino acid in a stereocontrolled route, involving C–C double bond functionalization by dihydroxylation, followed by oxidative ring cleavage and transformation of the