Issue 43, 2013
From the journal:

Organic & Biomolecular Chemistry

Is the 2,3-carbon–carbon bond of indole really inert to oxidative cleavage by Oxone? – Synthesis of isatoic anhydrides from indoles†

Amber C. Nelson,a   Emily S. Kalinowski,a   Nikolas J. Czerniecki,a   Taylor L. Jacobsona  and  Peter Grundt*a  

* Corresponding authors

a Department of Chemistry & Biochemistry, University of Minnesota Duluth, 1039 University Drive, Duluth, MN 55812, USA
E-mail: pgrundt@d.umn.edu

Abstract

A recent report has indicated that the oxidizing agent Oxone does not possess the ability to cleave the 2,3-carbon–carbon bond of indole. Work in our laboratory shows that this is not the case. Indole and a variety of aryl ring substituted derivatives readily react to form synthetically important isatoic anhydrides.

Graphical abstract: Is the 2,3-carbon–carbon bond of indole really inert to oxidative cleavage by Oxone? – Synthesis of isatoic anhydrides from indoles

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3OB41802B
Article type
Communication
Submitted
04 Sep 2013
Accepted
24 Sep 2013
First published
03 Oct 2013

Org. Biomol. Chem., 2013,11, 7455-7457

Permissions

Request permissions

Is the 2,3-carbon–carbon bond of indole really inert to oxidative cleavage by Oxone? – Synthesis of isatoic anhydrides from indoles

A. C. Nelson, E. S. Kalinowski, N. J. Czerniecki, T. L. Jacobson and P. Grundt, Org. Biomol. Chem., 2013, 11, 7455 DOI: 10.1039/C3OB41802B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements