Chemical motifs that redox cycle and their associated toxicity†
Abstract
Focussed screening of known redox cyclers, and structurally related compounds, was performed using a horseradish peroxidase–
* Corresponding authors
a Compound Safety Prediction, Pfizer Global R&D, Eastern Point Road, Groton CT, USA
b
Chemical Biology Group, BioTherapeutics Chemistry, WorldWide Medicinal Chemistry, Pfizer Global R&D, Cambridge, MA, USA
E-mail:
lyn.jones@pfizer.com
Tel: +1 617 665 5631
Focussed screening of known redox cyclers, and structurally related compounds, was performed using a horseradish peroxidase–
P. Rana, R. Naven, A. Narayanan, Y. Will and L. H. Jones, Med. Chem. Commun., 2013, 4, 1175 DOI: 10.1039/C3MD00149K
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