Issue 57, 2013
From the journal:

Chemical Communications

A new anti-cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles†

Wei-Hai Chen,‡a   Jing-Xiao Chen,‡a   Han Cheng,‡a   Chang-Sheng Chen,a   Juan Yang,a   Xiao-Ding Xu,a   Yan Wang,b   Ren-Xi Zhuoa  and  Xian-Zheng Zhang*a  

* Corresponding authors

a Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072
E-mail: xz-zhang@whu.edu.cn
Fax: +86 27 6875 4509
Tel: +86 27 6875 5993

b Analysis and Testing Center, Institute of hydrobiology, Chinese Academy of Science, Wuhan 430072, P. R. China

Abstract

Gold nanoparticles functionalized with pro-apoptotic peptide (PAP-AuNPs) were fabricated, which were able to lead to programmed cell-death by damaging mitochondria.

Graphical abstract: A new anti-cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles

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Article information

DOI
https://doi.org/10.1039/C3CC43283A
Article type
Communication
Submitted
03 May 2013
Accepted
04 Jun 2013
First published
04 Jun 2013

Chem. Commun., 2013,49, 6403-6405

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A new anti-cancer strategy of damaging mitochondria by pro-apoptotic peptide functionalized gold nanoparticles

W. Chen, J. Chen, H. Cheng, C. Chen, J. Yang, X. Xu, Y. Wang, R. Zhuo and X. Zhang, Chem. Commun., 2013, 49, 6403 DOI: 10.1039/C3CC43283A

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