Issue 33, 2013
From the journal:

Chemical Communications

Direct electrical single-molecule detection of DNA through electron transfer induced by hybridization†

Tomoaki Nishino*a  and  Phuc Tan Buib  

* Corresponding authors

a Nanoscience and Nanotechnology Research Center, Osaka Prefecture University, Sakai, Osaka 599-8570, Japan
E-mail: t-nishino@21c.osakafu-u.ac.jp
Fax: +81-72-254-8194
Tel: +81-72-254-8194

b Department of Materials Science, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan

Abstract

Single-stranded DNA was utilized as a probe tip for single-molecule DNA detection. Hybridization of the DNA tip and target DNA induces electron tunneling through the resulting DNA duplex. It is demonstrated that the DNA tip allows not only genetic detection but also discovery of single-nucleotide polymorphisms at the single-molecule level.

Graphical abstract: Direct electrical single-molecule detection of DNA through electron transfer induced by hybridization

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC38992H
Article type
Communication
Submitted
17 Dec 2012
Accepted
07 Mar 2013
First published
07 Mar 2013

Chem. Commun., 2013,49, 3437-3439

Permissions

Request permissions

Direct electrical single-molecule detection of DNA through electron transfer induced by hybridization

T. Nishino and P. T. Bui, Chem. Commun., 2013, 49, 3437 DOI: 10.1039/C3CC38992H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements