A practical method for the synthesis of 1,3-aminohydroxyacetone synthons was developed, and their utility in the organocatalytic asymmetric aldol reaction was demonstrated in a short synthesis of aza-sugars.
Y. Komatsu, R. Watanabe, H. Ikishima, K. Nakano, Y. Ichikawa and H. Kotsuki, Org. Biomol. Chem., 2012, 10, 2993 DOI: 10.1039/C2OB07107J
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