Issue 17, 2012
From the journal:

Lab on a Chip

Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics†

Yi Zhang,ab   Yunfang Tang,a   Yi-Heui Hsieh,c   Chuen-Yuan Hsu,c   Jianzhong Xi,b   Kuan-Jiuh Lin*c  and  Xingyu Jiang*a  

* Corresponding authors

a CAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, China
E-mail: xingyujiang@nanoctr.cn

b Department of Biomedical Engineering, College of Engineering, Peking University, Beijing, China

c Department of Chemistry, National Chung Hsing University, Taichung, Taiwan
E-mail: kjlin@dragon.nchu.edu.tw

Abstract

This work reports an integrated platform combining localized-surface plasmon resonance (LSPR) and microfluidic chips to carry out multiplexed and label-free protein analysis. We fabricated an optical bench to enable detection using only a laboratory UV-Vis spectrophotometer. This assay not only improves throughput, but also allows quantitative analysis.

Graphical abstract: Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics

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Article information

DOI
https://doi.org/10.1039/C2LC40590C
Article type
Communication
Submitted
13 Mar 2012
Accepted
28 May 2012
First published
31 May 2012

Lab Chip, 2012,12, 3012-3015

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Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics

Y. Zhang, Y. Tang, Y. Hsieh, C. Hsu, J. Xi, K. Lin and X. Jiang, Lab Chip, 2012, 12, 3012 DOI: 10.1039/C2LC40590C

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