Issue 97, 2012
From the journal:

Chemical Communications

Stabilization and enhanced reactivity of actinorhodinpolyketide synthase minimal complex in polymer–nucleotide coacervate droplets†

John Crosby,*a   Tom Treadwell,a   Michelle Hammerton,a   Konstantinos Vasilakis,a   Matthew P. Crump,a   David S. Williamsa  and  Stephen Mann*a  

* Corresponding authors

a School of Chemistry, University of Bristol, Bristol, UK
E-mail: john.crosby@bristol.ac.uk, s.mann@bristol.ac.uk

Abstract

Compartmentalization of the minimal complex of actinorhodin polyketide synthase in coacervate liquid droplets produces enhanced yields of shunt polyketides under conditions of low and high ionic strength.

Graphical abstract: Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer–nucleotide coacervate droplets

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Article information

DOI
https://doi.org/10.1039/C2CC36533B
Article type
Communication
Submitted
07 Sep 2012
Accepted
15 Oct 2012
First published
15 Oct 2012

Chem. Commun., 2012,48, 11832-11834

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Stabilization and enhanced reactivity of actinorhodin polyketide synthase minimal complex in polymer–nucleotide coacervate droplets

J. Crosby, T. Treadwell, M. Hammerton, K. Vasilakis, M. P. Crump, D. S. Williams and S. Mann, Chem. Commun., 2012, 48, 11832 DOI: 10.1039/C2CC36533B

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