Issue 7, 2012
From the journal:

Chemical Communications

Exonuclease-assisted cascaded recycling amplification for label-free detection ofDNA†

Sai Bi,*a   Li Lia  and  Yangyang Cuia  

* Corresponding authors

a State Key Laboratory Base of Eco-chemical Engineering, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China
E-mail: bisai11@126.com
Fax: +86 532 84022750
Tel: +86 532 84022946

Abstract

The network consisting of three kinds of unlabeled stem-loop DNA molecular beacons (MBs) is activated by target DNA in the presence of exonuclease-III (Exo-III), achieving the concept of exonuclease-assisted cascaded recycling amplification (Exo-CRA) for DNA detection with a wide dynamic range of 8 orders of magnitude.

Graphical abstract: Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA

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Article information

DOI
https://doi.org/10.1039/C1CC16684K
Article type
Communication
Submitted
28 Oct 2011
Accepted
21 Nov 2011
First published
21 Nov 2011

Chem. Commun., 2012,48, 1018-1020

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Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA

S. Bi, L. Li and Y. Cui, Chem. Commun., 2012, 48, 1018 DOI: 10.1039/C1CC16684K

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