Issue 5, 2011

Facile one-pot synthesis of polymer–phospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

Abstract

This paper reports the one-pot synthesis of perfluorocarbon microbubbles with crosslinked shells of poly(acrylic acid) and phospholipid that boast excellent ultrasound contrast enhancement, enhanced loading capacity, and the ability to retain or release their contents through variation in the level of ultrasound exposure.

Graphical abstract: Facile one-pot synthesis of polymer–phospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

Supplementary files

Article information

Article type
Communication
Submitted
09 Oct 2010
Accepted
03 Jan 2011
First published
24 Jan 2011

Soft Matter, 2011,7, 1656-1659

Facile one-pot synthesis of polymerphospholipid composite microbubbles with enhanced drug loading capacity for ultrasound-triggered therapy

M. A. Nakatsuka, J. H. Lee, E. Nakayama, A. M. Hung, M. J. Hsu, R. F. Mattrey, S. C. Esener, J. N. Cha and A. P. Goodwin, Soft Matter, 2011, 7, 1656 DOI: 10.1039/C0SM01131B

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