Issue 36, 2011

A fluoro analogue of UDP-α-d-glucuronic acid is an inhibitor of UDP-α-d-apiose/UDP-α-d-xylose synthase

Abstract

UDP-2F-glucuronic acid was synthesized and analyzed as a mechanistic probe to investigate the ring contraction step catalyzed by UDP-D-apiose/UDP-D-xylose synthase (AXS).

Graphical abstract: A fluoro analogue of UDP-α-d-glucuronic acid is an inhibitor of UDP-α-d-apiose/UDP-α-d-xylose synthase

Supplementary files

Article information

Article type
Communication
Submitted
27 May 2011
Accepted
20 Jul 2011
First published
09 Aug 2011

Chem. Commun., 2011,47, 10130-10132

A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-apiose/UDP-α-D-xylose synthase

S. Choi, M. W. Ruszczycky, H. Zhang and H. Liu, Chem. Commun., 2011, 47, 10130 DOI: 10.1039/C1CC13140K

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