Issue 1, 2011

The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch

Abstract

By applying four different acid derivatives of vitamin B12, we demonstrate that the H-bonding pattern and the electrostatic environment provided by each side chain of the corrin ring are crucial for the correct structural rearrangement of the btuBriboswitch of E. coli.

Graphical abstract: The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch

Supplementary files

Article information

Article type
Communication
Submitted
08 Jul 2010
Accepted
17 Aug 2010
First published
10 Sep 2010

Chem. Commun., 2011,47, 403-405

The change of corrin-amides to carboxylates leads to altered structures of the B12-responding btuBriboswitch

S. Gallo, S. Mundwiler, R. Alberto and R. K. O. Sigel, Chem. Commun., 2011, 47, 403 DOI: 10.1039/C0CC02447C

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