Issue 1, 2011
From the journal:

Photochemical & Photobiological Sciences

Tailoring silver nanodots for intracellular staining

Sungmoon Choi,a   Junhua Yu,†a   Sandeep A. Patel,a   Yih-Ling Tzeng*b  and  Robert M. Dickson*a  

* Corresponding authors

a School of Chemistry and Biochemistry and Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, GA, USA
E-mail: dickson@chemistry.gatech.edu

b Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
E-mail: ytzeng@emory.edu

Abstract

Through tailored oligonucleotide scaffolds, Ag nanocluster syntheses have yielded thermally and cell-culture medium stable silver cluster-based emitters. Optimizing ssDNA stability has enabled creation of highly concentrated and spectrally pure nanocluster emitters with strong intracellular emission. Both fixed and live-cell staining become possible, and intracellular delivery is demonstrated both through conjugation to cell-penetrating peptides and via microinjection.

Graphical abstract: Tailoring silver nanodots for intracellular staining

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Article information

DOI
https://doi.org/10.1039/C0PP00263A
Article type
Paper
Submitted
20 Aug 2010
Accepted
19 Oct 2010
First published
09 Nov 2010

Photochem. Photobiol. Sci., 2011,10, 109-115

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Tailoring silver nanodots for intracellular staining

S. Choi, J. Yu, S. A. Patel, Y. Tzeng and R. M. Dickson, Photochem. Photobiol. Sci., 2011, 10, 109 DOI: 10.1039/C0PP00263A

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