Diastereoselective assembly of pentanuclear circular helicates

Abstract

Reaction of a ligand which contains two N-donor and O-donor tridentate domains separated by a 1,3-phenylene spacer unit with Zn²⁺ ions results in a pentanuclear circular helicate [Zn₅(L)₅]¹⁰⁺ and this structure persists in both the solid and solution state. The formation of this high nuclearity species is governed by unfavourable steric interactions between the phenyl units which destabilize the simple linear helicate. Incorporation of enantiopure units within the ligand strand controls the diastereoselectivity with up to 80% d.e.