Issue 12, 2011

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Abstract

This review provides an overview of a relatively new class of bio-conjugates, DNA amphiphiles, which consist of oligonucleotides covalently bonded to synthetic hydrophobic units. The reader will find the basic principles for the structural design and preparation methods of the materials. Moreover, the self-assembly into superstructures of higher order will be highlighted. Finally, some potential applications will be described.

Graphical abstract: Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

Article information

Article type
Tutorial Review
Submitted
24 May 2011
First published
22 Aug 2011

Chem. Soc. Rev., 2011,40, 5745-5755

Nucleic acid amphiphiles: synthesis and self-assembled nanostructures

M. Kwak and A. Herrmann, Chem. Soc. Rev., 2011, 40, 5745 DOI: 10.1039/C1CS15138J

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