Issue 17, 2011
From the journal:

Physical Chemistry Chemical Physics

DMF-exfoliated graphene for electrochemical NADH detection

Gareth P. Keeley,*abc   Arlene O'Neill,bd   Michael Holzinger,a   Serge Cosnier,a   Jonathan N. Colemanbd  and  Georg S. Duesbergbc  

* Corresponding authors

a Département de Chimie Moléculaire, UMR 5250, ICMG FR 2607, CNRS, Université Joseph Fourier, BP 53, 38041 Grenoble cedex 9, France
E-mail: gkeeley@ujf-grenoble.fr
Fax: +33 4 5652 0805
Tel: +33 4 5652 0853

b Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Dublin 2, Ireland

c School of Chemistry, Trinity College, Dublin 2, Ireland

d School of Physics, Trinity College, Dublin 2, Ireland

Abstract

The electrochemical detection of NADH is of considerable interest because it is required as a cofactor in a large number of dehydrogenase-based biosensors. However, the presence of oxygenated functionalities on the electrode often causes fouling due to the adsorption of the oxidised form, NAD+. Here we report an electroanalytical NADH sensor based on DMF-exfoliated graphene. The latter is shown to have a very low oxygen content, facilitating the exceptionally stable and sensitive detection of this important analyte.

Graphical abstract: DMF-exfoliated graphene for electrochemical NADH detection

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/C1CP20060G
Article type
Communication
Submitted
07 Jan 2011
Accepted
07 Mar 2011
First published
22 Mar 2011

Phys. Chem. Chem. Phys., 2011,13, 7747-7750

Permissions

Request permissions

DMF-exfoliated graphene for electrochemical NADH detection

G. P. Keeley, A. O'Neill, M. Holzinger, S. Cosnier, J. N. Coleman and G. S. Duesberg, Phys. Chem. Chem. Phys., 2011, 13, 7747 DOI: 10.1039/C1CP20060G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements