Issue 38, 2011
From the journal:

Chemical Communications

A graphene oxide–peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2†

Duan Feng,a   Yangyang Zhang,a   Tingting Feng,a   Wen Shi,a   Xiaohua Lia  and  Huimin Ma*a  

* Corresponding authors

a Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China
E-mail: mahm@iccas.ac.cn
Fax: +86-10-62559373
Tel: +86-10-62554673

Abstract

A graphene oxide–peptide based fluorescence sensor has been developed for matrix metalloproteinase 2 (MMP2), and its applicability has been demonstrated by monitoring the concentration of MMP2 secreted by HeLa cells, revealing that HeLa cells with a density of 5.48 × 105cells per mL can produce 22 nM in cell culture media in 24 h.

Graphical abstract: A graphene oxide–peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2

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Article information

DOI
https://doi.org/10.1039/C1CC13975D
Article type
Communication
Submitted
04 Jul 2011
Accepted
16 Aug 2011
First published
02 Sep 2011

Chem. Commun., 2011,47, 10680-10682

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A graphene oxide–peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2

D. Feng, Y. Zhang, T. Feng, W. Shi, X. Li and H. Ma, Chem. Commun., 2011, 47, 10680 DOI: 10.1039/C1CC13975D

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