Issue 32, 2011
From the journal:

Chemical Communications

Indium mediated allylation in peptide and protein functionalization†

Jenefer Alam,a   Thomas H. Kellera  and  Teck-Peng Loh*a  

* Corresponding authors

a Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, 1 Nanyang Walk, Block 5 Level 3, Nanyang Technological University, Singapore 637371, Singapore
E-mail: teckpeng@ntu.edu.sg
Fax: +65 6515 8229
Tel: +65 6316 8899

Abstract

Indium-mediated allylation has been used in the site-selective functionalization of N-terminal aldehydes of peptides and proteins. This is the first demonstration of indium-mediated C–C bond formation in protein labelling studies under mild and environmentally friendly conditions.

Graphical abstract: Indium mediated allylation in peptide and protein functionalization

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Article information

DOI
https://doi.org/10.1039/C1CC12926K
Article type
Communication
Submitted
18 May 2011
Accepted
27 Jun 2011
First published
14 Jul 2011

Chem. Commun., 2011,47, 9066-9068

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Indium mediated allylation in peptide and protein functionalization

J. Alam, T. H. Keller and T. Loh, Chem. Commun., 2011, 47, 9066 DOI: 10.1039/C1CC12926K

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