Issue 12, 2011
From the journal:

Chemical Communications

Ultrasensitive fluorescence polarization DNA detection by target assisted exonuclease III-catalyzed signal amplification†

Min Zhang,a   Yi-Meng Guana  and  Bang-Ce Ye*a  

* Corresponding authors

a Lab of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology, Meilong RD 130, Shanghai, China
E-mail: bcye@ecust.edu.cn
Fax: +86 2164252094

Abstract

Single stranded DNA sequences can be detected by target assisted exonuclease III-catalyzed signal amplification fluorescence polarization (TAECA-FP). The method offers an impressive detection limit of 83 aM within one hour for DNA detection and exhibits high discrimination ability even against a single base mismatch.

Graphical abstract: Ultrasensitive fluorescence polarization DNA detection by target assisted exonuclease III-catalyzed signal amplification

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0CC05703G
Article type
Communication
Submitted
21 Dec 2010
Accepted
20 Jan 2011
First published
08 Feb 2011

Chem. Commun., 2011,47, 3478-3480

Permissions

Request permissions

Ultrasensitive fluorescence polarization DNA detection by target assisted exonuclease III-catalyzed signal amplification

M. Zhang, Y. Guan and B. Ye, Chem. Commun., 2011, 47, 3478 DOI: 10.1039/C0CC05703G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements