Issue 20, 2010
From the journal:

Organic & Biomolecular Chemistry

Asymmetric transfer hydrogenation of ketones catalyzed by rhodium complexes containing amino acid triazole ligands†

Fredrik Tinnisa  and  Hans Adolfsson*a  

* Corresponding authors

a Department of Organic Chemistry, Stockholm University, The Arrhenius Laboratory, SE-10691 Stockholm, Sweden
E-mail: hansa@organ.su.se
Fax: (+) 46-8-154908
Tel: (+) 46-8-162484

Abstract

Active and selective catalysts for the asymmetric reduction of ketones, under transfer hydrogenation conditions, were obtained by combining [RhCl2Cp*]2, with a series of L-amino acid thioamide ligands functionalized with 1,2,3-triazoles. The obtained secondary alcohol products were formed with up to 93% ee.

Graphical abstract: Asymmetric transfer hydrogenation of ketones catalyzed by rhodium complexes containing amino acid triazole ligands

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C0OB00400F
Article type
Communication
Submitted
08 Jul 2010
Accepted
06 Aug 2010
First published
19 Aug 2010

Org. Biomol. Chem., 2010,8, 4536-4539

Permissions

Request permissions

Asymmetric transfer hydrogenation of ketones catalyzed by rhodium complexes containing amino acid triazole ligands

F. Tinnis and H. Adolfsson, Org. Biomol. Chem., 2010, 8, 4536 DOI: 10.1039/C0OB00400F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements