Issue 5, 2010
From the journal:

Organic & Biomolecular Chemistry

Total synthesis of (+)-chloriolide†

Timm T. Hauga  and  Stefan F. Kirsch*a  

* Corresponding authors

a Department Chemie, Technische Universität München, Lichtenbergstr. 4, 85747 Garching, Germany
E-mail: stefan.kirsch@ch.tum.de
Fax: (+49) 89-2891-3315

Abstract

The first total synthesis of (+)-chloriolide, a 12-membered macrolide from Chloridium virescens (var. chlamydosporum), was accomplished in a longest linear sequence of 20 steps from commercial materials in 7% overall yield.

Graphical abstract: Total synthesis of (+)-chloriolide

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Article information

DOI
https://doi.org/10.1039/B925644J
Article type
Communication
Submitted
08 Dec 2009
Accepted
21 Dec 2009
First published
08 Jan 2010

Org. Biomol. Chem., 2010,8, 991-993

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Total synthesis of (+)-chloriolide

T. T. Haug and S. F. Kirsch, Org. Biomol. Chem., 2010, 8, 991 DOI: 10.1039/B925644J

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