Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity†‡
Abstract
The synthesis of the first spacer containing, duocarmycin analogue
* Corresponding authors
a
Institut for Organic and Biomolecular Chemistry, Georg-August-University Göttingen, Tammannstrasse 2, Göttingen, Germany
E-mail:
ltietze@gwdg.de
Fax: +49(0)551-399476
b Centre of Internal Medicine, Department of Haematology and Oncology of the Georg-August-University of Göttingen, Robert-Koch-Straße 40, Göttingen, Germany
The synthesis of the first spacer containing, duocarmycin analogue
H. J. Schuster, B. Krewer, J. M. von Hof, K. Schmuck, I. Schuberth, F. Alves and L. F. Tietze, Org. Biomol. Chem., 2010, 8, 1833 DOI: 10.1039/B925070K
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