Issue 14, 2010
From the journal:

Journal of Materials Chemistry

Cancer-cell targeting and cell-specific delivery by mesoporous silicananoparticles

Jessica Rosenholm,a   Cecilia Sahlgren*bc  and  Mika Lindén*a  

* Corresponding authors

a Center for Functional Materials, Department of Physical Chemistry, Åbo Akademi University, Porthansgatan 3-5, Turku, Finland
E-mail: mlinden@abo.fi

b Department of Biology, Åbo Akademi University, Artillerigatan 6A, Turku, Finland
E-mail: csahlgre@abo.fi

c Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, P.O. Box 123, Turku, Finland

Abstract

Mesoporous silica nanoparticles (MSNs) have emerged as promising drug carriers. Here we highlight some recent developments related to cell-specific targeting and delivery using MSNs. Some key requirements for carrier design are discussed from a biological perspective, including a suggested experimental work-flow for the evaluation of active cell-specific targeting of nanoparticles.

Graphical abstract: Cancer-cell targeting and cell-specific delivery by mesoporous silica nanoparticles

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Article information

DOI
https://doi.org/10.1039/B920076B
Article type
Highlight
Submitted
28 Sep 2009
Accepted
07 Dec 2009
First published
25 Jan 2010

J. Mater. Chem., 2010,20, 2707-2713

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Cancer-cell targeting and cell-specific delivery by mesoporous silica nanoparticles

J. Rosenholm, C. Sahlgren and M. Lindén, J. Mater. Chem., 2010, 20, 2707 DOI: 10.1039/B920076B

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