Issue 9, 2010
From the journal:

Chemical Communications

Synthesis of AZT-based cationic lipids and in vitro evaluation of siRNA delivery†

Sun Min Park,a   Jungeun Woo,a   Eunmi Jeona  and  Byeang Hyean Kim*a  

* Corresponding authors

a Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, South Korea
E-mail: bhkim@postech.ac.kr
Fax: +82 54-279-3399
Tel: +82 54-279-5856

Abstract

New types of cationic lipids based on AZT were evaluated for their biological effects in terms of their cytotoxicity and their cellular delivery of siRNA.

Graphical abstract: Synthesis of AZT-based cationic lipids and in vitro evaluation of siRNA delivery

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Article information

DOI
https://doi.org/10.1039/B919845H
Article type
Communication
Submitted
23 Sep 2009
Accepted
17 Dec 2009
First published
20 Jan 2010

Chem. Commun., 2010,46, 1523-1525

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Synthesis of AZT-based cationic lipids and in vitro evaluation of siRNA delivery

S. M. Park, J. Woo, E. Jeon and B. H. Kim, Chem. Commun., 2010, 46, 1523 DOI: 10.1039/B919845H

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