A new chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins

Lomary S. Moon; Ravinder S. Jolly; Yoganjaneyulu Kasetti; Prasad V. Bharatam

doi:10.1039/B817800C

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A new chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins†

Lomary S. Moon,^a Ravinder S. Jolly,*^a Yoganjaneyulu Kasetti^b and Prasad V. Bharatam^b

Author affiliations

* Corresponding authors

^a Department of Chemistry, Institute of Microbial Technology, Sector 39, India
E-mail: jolly@imtech.res.in
Fax: +91 172-2690632
Tel: +91 172-2636680

^b Department of Medicinal Chemistry, National Institute of Pharma Education and Research, Sector 67, Punjab, India

Abstract

Optically active mandelic acid in the presence of dimethylaminopyridine is an excellent chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins.

Download options Please wait...

Supplementary files

Methods, Job's plot, NMR titration curves, Cartesiancoordinates for the models in Fig. 2 and Fig. 3, and NMR spectrafor all of the entries in Table 1 and Table 2 PDF (6299K)

Article information

DOI: https://doi.org/10.1039/B817800C
Article type: Communication
Submitted: 09 Oct 2008
Accepted: 24 Nov 2008
First published: 05 Jan 2009

Download Citation

Chem. Commun., 2009, 1067-1069

Permissions

Request permissions

A new chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins

L. S. Moon, R. S. Jolly, Y. Kasetti and P. V. Bharatam, Chem. Commun., 2009, 1067 DOI: 10.1039/B817800C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

A new chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins†

Abstract

Supplementary files

Article information

Download Citation

Permissions

A new chiral shift reagent for the determination of enantiomeric excess and absolute configuration in cyanohydrins

Social activity

Search articles by author

Spotlight

Advertisements