Issue 43, 2009

Dynamic kinetic resolution in the asymmetric synthesis of atropisomeric biaryl[4] and [5]helicene quinones

Abstract

Total control of axial and helical chirality elements of a (2-biphenyl)-substituted tetrahydro[5]helicene quinone and the configurationally stable dihydro[4]helicene analogue was achieved in a dynamic kinetic resolution process of an axially chiral racemic diene promoted by an enantiopure sulfinyl benzoquinone.

Graphical abstract: Dynamic kinetic resolution in the asymmetric synthesis of atropisomeric biaryl[4] and [5]helicene quinones

Supplementary files

Article information

Article type
Communication
Submitted
17 Apr 2009
Accepted
11 Sep 2009
First published
25 Sep 2009

Chem. Commun., 2009, 6652-6654

Dynamic kinetic resolution in the asymmetric synthesis of atropisomeric biaryl[4] and [5]helicene quinones

A. Latorre, A. Urbano and M. C. Carreño, Chem. Commun., 2009, 6652 DOI: 10.1039/B907653K

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