Issue 36, 2008
From the journal:

Chemical Communications

Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines†

Minjeong So,a   John B. Schenkmanb  and  James F. Rusling*ab  

* Corresponding authors

a Department of Chemistry, University of Connecticut, USA
E-mail: james.rusling@uconn.edu

b Department of Cell Biology, University of Connecticut, USA

Abstract

We demonstrate for the first time a biosensor featuring a sequential two-enzyme pathway suitable to screen potentially toxic reactive metabolites generated during metabolism.

Graphical abstract: Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines

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Article information

DOI
https://doi.org/10.1039/B805447A
Article type
Communication
Submitted
01 Apr 2008
Accepted
10 Jun 2008
First published
18 Jul 2008

Chem. Commun., 2008, 4354-4356

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Electrochemical biosensor featuring a two-enzyme pathway and DNA for screening toxic reactive metabolites of arylamines

M. So, J. B. Schenkman and J. F. Rusling, Chem. Commun., 2008, 4354 DOI: 10.1039/B805447A

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