Issue 43, 2007

Nano-particle labelling of nucleic acids for enhanced detection by inductively-coupled plasma mass spectrometry (ICP-MS)

Abstract

Oligonucleotides containing a biotin functionality were successfully labelled with a streptavidin nanogold conjugate and subsequently separated and analysed by high performance liquid chromatography–inductively coupled plasma–mass spectrometry (HPLC-ICP-MS).

Graphical abstract: Nano-particle labelling of nucleic acids for enhanced detection by inductively-coupled plasma mass spectrometry (ICP-MS)

Article information

Article type
Communication
Submitted
22 Jun 2007
Accepted
07 Sep 2007
First published
14 Sep 2007

Chem. Commun., 2007, 4537-4539

Nano-particle labelling of nucleic acids for enhanced detection by inductively-coupled plasma mass spectrometry (ICP-MS)

S. L. Kerr and B. Sharp, Chem. Commun., 2007, 4537 DOI: 10.1039/B709466C

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