Issue 21, 2006

Easy access to the family of thiazole N-oxides using HOF·CH3CN

Abstract

An efficient procedure for transferring an oxygen atom to thiazole-containing compounds, resulting in the corresponding N-oxides, was developed by using HOF·CH3CN; mild reaction conditions, high yields and easy purification are the main features of this novel route, while X-ray structural analysis reveals a hydrogen bond between the N-oxide functionality and a water molecule.

Graphical abstract: Easy access to the family of thiazole N-oxides using HOF·CH3CN

Supplementary files

Article information

Article type
Communication
Submitted
21 Feb 2006
Accepted
05 Apr 2006
First published
25 Apr 2006

Chem. Commun., 2006, 2262-2264

Easy access to the family of thiazole N-oxides using HOF·CH3CN

E. Amir and S. Rozen, Chem. Commun., 2006, 2262 DOI: 10.1039/B602594C

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