Issue 10, 2005

Writing 3D protein nanopatterns onto a silicon nanosponge

Abstract

A three-dimensional protein nanopatterning method has been developed, based on local activation of porous silicon by electron beam. Proteins specifically bind to irradiated regions, and the depth of biomolecule nanopatterns can be controlled by varying the electron energy. This unique feature permits exploitation of the huge surface area of the sponge-like material, thus allowing concentration of a large amount of proteins on nanosized patterns. Moreover, the grafted biomolecules retain their full functionality, and the feasibility of a glucose sensor has been demonstrated.

Graphical abstract: Writing 3D protein nanopatterns onto a silicon nanosponge

Supplementary files

Article information

Article type
Paper
Submitted
12 Apr 2005
Accepted
19 Aug 2005
First published
02 Sep 2005

Lab Chip, 2005,5, 1048-1052

Writing 3D protein nanopatterns onto a silicon nanosponge

S. Borini, S. D'Auria, M. Rossi and A. M. Rossi, Lab Chip, 2005, 5, 1048 DOI: 10.1039/B505089H

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