Critical care analyzer with fluorescent optical chemosensors for blood analytes

Abstract

This article summarizes the application of fluorescent sensors to in vitro diagnostic systems measuring critical care analytes in whole blood. We discuss recent advances in fluorescent chemosensor technologies employing fluorescence indicators used for this application. This paper touches on key materials, structure–property relations, and design considerations for maximum utility in low-cost portable systems. In this application the optical sensor technology demonstrates precision and stability comparable or better than that of the best-available conventional technologies employing electrochemical sensors.