Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems

T. Benvegnu; G. Réthoré; M. Brard; W. Richter; D. Plusquellec

doi:10.1039/B511440C

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems†

T. Benvegnu,*^a G. Réthoré,^a M. Brard,^a W. Richter^b and D. Plusquellec^a

Author affiliations

* Corresponding authors

^a ENSCR UMR CNRS 6052, Laboratoire “Synthèses et Activations de Biomolécules”, Institut de Chimie de Rennes, Avenue du Général Leclerc, Rennes, France
E-mail: Thierry.Benvegnu@ensc_rennes.fr

^b Elektronenmikroskopisches Zentrum, Universitätsklinikum Jena, Ziegelmühlenweg 1, Jena, Germany

Abstract

The in vitro stability of archaeosomes made from novel synthetic membrane-spanning tetraether lipids was evaluated in conditions mimicking those of oral route application in terms of bile salts, serum and low pH..

Download options Please wait...

Supplementary files

Percent leakage of encapsulated CF from liposomes prepared from increasing proportions of lipids 1 or 5, in a 0.4% sodium cholate KRB buffer solution or upon exposure (37 ?C) to fetal bovine serum PDF (133K)

Article information

DOI: https://doi.org/10.1039/B511440C
Article type: Communication
Submitted: 11 Aug 2005
Accepted: 15 Sep 2005
First published: 10 Oct 2005

Download Citation

Chem. Commun., 2005, 5536-5538

Permissions

Request permissions

Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems

T. Benvegnu, G. Réthoré, M. Brard, W. Richter and D. Plusquellec, Chem. Commun., 2005, 5536 DOI: 10.1039/B511440C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Chemical Communications

Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Archaeosomes based on novel synthetic tetraether-type lipids for the development of oral delivery systems

Social activity

Search articles by author

Spotlight

Advertisements