Issue 24, 2004
From the journal:

Chemical Communications

TAT conjugated, FITC doped silica nanoparticles for bioimaging applications†

Swadeshmukul Santra,*ab   Heesun Yang,c   Debamitra Dutta,b   Jessie T. Stanley,a   Paul H. Holloway,c   Weihong Tan,d   Brij M. Moudgilbc  and  Robert A. Mericlea  

* Corresponding authors

a Department of Neurological Surgery, University of Florida, PO Box 100265, Gainesville, USA
E-mail: santra@neurosurgery.ufl.edu
Fax: (352) 392-8413
Tel: (352) 392-4331

b Particle Engineering Research Center, University of Florida, PO Box 116135, Gainesville, USA

c Department of Materials Science and Engineering, University of Florida, PO Box 116400, USA

d Department of Chemistry, University of Florida, PO Box 117200, Gainesville, USA

Abstract

Water-in-oil (w/o) microemulsion synthesis of 70 nm size monodisperse TAT (a cell penetrating peptide, CPP) conjugated, FITC (fluorescein isothiocyanate) doped silica nanoparticles (TAT-FSNPs) is reported; human lung adenocarcinoma (A549) cells (in vitro) and rat brain tissue (in vivo) were successfully labeled using TAT-FSNPs.

Graphical abstract: TAT conjugated, FITC doped silica nanoparticles for bioimaging applications

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Article information

DOI
https://doi.org/10.1039/B411916A
Article type
Communication
Submitted
03 Aug 2004
Accepted
22 Sep 2004
First published
25 Oct 2004

Chem. Commun., 2004, 2810-2811

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TAT conjugated, FITC doped silica nanoparticles for bioimaging applications

S. Santra, H. Yang, D. Dutta, J. T. Stanley, P. H. Holloway, W. Tan, B. M. Moudgil and R. A. Mericle, Chem. Commun., 2004, 2810 DOI: 10.1039/B411916A

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