Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases†
Abstract
Antisense
* Corresponding authors
a
Department of Bioorganic Chemistry, Biomedical Center, University of Uppsala, Box 581, S-751 23 Uppsala, Sweden
E-mail:
jyoti@boc.uu.se
Fax: +4618554495
Antisense
Pushpangadan. I. Pradeepkumar, N. V. Amirkhanov and J. Chattopadhyaya, Org. Biomol. Chem., 2003, 1, 81 DOI: 10.1039/B210163G
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