Issue 2, 2003
From the journal:

Organic & Biomolecular Chemistry

Ring forming reactions of imines of 2-aminobenzaldehyde and related compounds

Per Wiklunda  and  Jan Bergman*a  

* Corresponding authors

a Unit for Organic Chemistry, Department of Biosciences, Karolinska Institute and Södertörn University College, Novum Research Park, SE-141 57 Huddinge, SWEDEN
E-mail: Jan.Bergman@biosci.ki.se

Abstract

By addition of organometallic reagents to 2-aminobenzonitriles followed by quenching with suitable electrophiles (acyl halides, aldehydes and ketones), several types of 6-membered benzofused aromatic and non-aromatic nitrogen heterocycles could be obtained. Rearrangements leading to 1,2-dihydro-3H-1,4-benzodiazepin-3-ones and preparation of various quinazolines are described.

Graphical abstract: Ring forming reactions of imines of 2-aminobenzaldehyde and related compounds

About
Cited by
Related
Download options Please wait...

Article information

DOI
https://doi.org/10.1039/B209505J
Article type
Paper
Submitted
27 Sep 2002
Accepted
07 Nov 2002
First published
09 Dec 2002

Org. Biomol. Chem., 2003,1, 367-372

Permissions

Request permissions

Ring forming reactions of imines of 2-aminobenzaldehyde and related compounds

P. Wiklund and J. Bergman, Org. Biomol. Chem., 2003, 1, 367 DOI: 10.1039/B209505J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements