Issue 5, 2003

Rapid microwave-promoted Suzuki cross coupling reaction in water

Abstract

Water is an inexpensive and nontoxic reaction medium for the microwave-promoted Suzuki cross coupling of arylboronic acids with aryl halides. This environmentally friendly microwave protocol offers convenient operation and synthesis of a variety of substituted biaryls in good yield very rapidly employing PdCl2(PPh3)2 as catalyst and potassium carbonate as the base.

Graphical abstract: Rapid microwave-promoted Suzuki cross coupling reaction in water

Article information

Article type
Paper
Submitted
08 May 2003
First published
04 Aug 2003

Green Chem., 2003,5, 615-617

Rapid microwave-promoted Suzuki cross coupling reaction in water

L. Bai, J. Wang and Y. Zhang, Green Chem., 2003, 5, 615 DOI: 10.1039/B305191A

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