Issue 21, 2002
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Reactions of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile with copper(ii) acetate: synthesis of 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles

Sangmin Yuna  and  Kyongtae Kim*a  

* Corresponding authors

a School of Chemistry and Molecular Engineering, Seoul National University, Seoul 151-742, Korea
E-mail: kkim@plaza.snu.ac.kr.
Fax: 82 2874 8858
Tel: 82 2880 6636

Abstract

Treatment of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile 15, prepared by reactions of N-aryl α-cyanoenamines 3 with Cu(OAc)2·H2O (2 equiv.) in the presence of pyridine (2 equiv.) in EtOH at reflux, and with Cu(OAc)2·H2O (1 equiv.) in HOAc at reflux gave 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles 11 in moderate to good yields.

Graphical abstract: Reactions of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile with copper(ii) acetate: synthesis of 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles

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Article information

DOI
https://doi.org/10.1039/B207530J
Article type
Paper
Submitted
01 Aug 2002
Accepted
13 Sep 2002
First published
07 Oct 2002

J. Chem. Soc., Perkin Trans. 1, 2002, 2360-2369

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Reactions of 2-[(2-arylimino-2-cyano-1,1-dimethylethyl)arylamino]-3-methylbut-2-enenitrile with copper(II) acetate: synthesis of 2-(2,3-dihydro-2,2-dimethyl-3-oxo-1H-indol-1-yl)-3-methylbut-2-enenitriles

S. Yun and K. Kim, J. Chem. Soc., Perkin Trans. 1, 2002, 2360 DOI: 10.1039/B207530J

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