Issue 6, 2002

Reduction of α-aryloxy carbonyl compounds with samarium(ii) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

Abstract

A new linker for the solid phase synthesis of functionalised carbonyl compounds which is cleaved under mild, neutral conditions using samarium(II) iodide has been developed; the manipulation of an immobilised γ-butyrolactone has been carried out to illustrate the utility of the linker.

Graphical abstract: Reduction of α-aryloxy carbonyl compounds with samarium(ii) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

Article information

Article type
Communication
Submitted
09 Jan 2002
Accepted
31 Jan 2002
First published
18 Feb 2002

Chem. Commun., 2002, 584-585

Reduction of α-aryloxy carbonyl compounds with samarium(II) iodide. A new traceless linker for the solid phase synthesis of carbonyl compounds

F. McKerlie, D. J. Procter and G. Wynne, Chem. Commun., 2002, 584 DOI: 10.1039/B200365C

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