Issue 21, 2001
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Synthesis and applications to asymmetric catalysis of a series of mono- and bis(diazaphospholidine) ligands

Donald Smyth,a   Heather Tye,a   Colin Eldred,b   Nathaniel W. Alcocka  and  Martin Willsa  

a Department of Chemistry, University of Warwick, Coventry, UK

b Glaxo-Wellcome Research and Development Ltd, Glaxo-Wellcome Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, UK

Abstract

The synthesis of a series of closely related mono- and bis(diazaphospholidine) ligands has been achieved using the condensation of a diamine with a bis(dimethylamino)arylphosphine. The resulting ligands have given excellent results in palladium-catalysed allylic substitution reactions to form C–C bonds (up to 89% ee) and C–N bonds (up to 78% ee).

Graphical abstract: Synthesis and applications to asymmetric catalysis of a series of mono- and bis(diazaphospholidine) ligands

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/B106399P
Article type
Paper
Submitted
18 Jul 2001
Accepted
13 Sep 2001
First published
12 Oct 2001

J. Chem. Soc., Perkin Trans. 1, 2001, 2840-2849

Permissions

Request permissions

Synthesis and applications to asymmetric catalysis of a series of mono- and bis(diazaphospholidine) ligands

D. Smyth, H. Tye, C. Eldred, N. W. Alcock and M. Wills, J. Chem. Soc., Perkin Trans. 1, 2001, 2840 DOI: 10.1039/B106399P

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements