Studies on the asymmetric reduction of β-oximino methyl etherboronates: reagent control, double diastereocontrol and transmitted remote asymmetric induction
Abstract
High asymmetric induction (94% ee) could be obtained in the reduction of the achiral E-oxime ether boronate 5 with a homochiral oxazaborolidine 13–BH3–THF complex. Application of this homochiral