Issue 10, 2000
From the journal:

Physical Chemistry Chemical Physics

Interaction of divalent metal ions with DNA investigated by 23Na NMR relaxation

Flaminia Cesare Marincola,a   Mariano Casu,a   Giuseppe Saba,a   Cesare Manettib  and  Adolfo Laia  

a Dipartimento di Scienze Chimiche, Università di Cagliari, Cittadella Universitaria di Monserrato, Monserrato (CA), Italy

b Dipartimento di Chimica, Università di Roma ‘‘La Sapienza’’, Roma, Italy

Abstract

The interaction between Na-DNA and divalent metal cations (Mg2+, Mn2+, Co2+ and Ni2+) has been investigated by 23Na NMR relaxation. The experimental data have been interpreted in terms of Manning's counterion condensation theory and a two-site exchange for the sodium ions. The experiments showed that Mn2+ affects the polyion surface atmosphere in a different way from the other metal ions. This behaviour may be due to sugar puckering transition of the DNA induced by Mn2+.

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Article information

DOI
https://doi.org/10.1039/B000433M
Article type
Paper
Submitted
17 Jan 2000
Accepted
06 Mar 2000
First published
11 Apr 2000

Phys. Chem. Chem. Phys., 2000,2, 2425-2428

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Interaction of divalent metal ions with DNA investigated by 23Na NMR relaxation

F. C. Marincola, M. Casu, G. Saba, C. Manetti and A. Lai, Phys. Chem. Chem. Phys., 2000, 2, 2425 DOI: 10.1039/B000433M

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