A general and efficient procedure for the preparation of enantiopure anti-1,2-diols—synthesis and utility of (R′,R′,S,R)-2,3-butane diacetal protected butane tetrol
Abstract
The synthesis and utility of 2,3-butane diacetal protected butane tetrol (R′,R′,R,S)-2 for the general and efficient production of enantiopure anti-1,2-diols through selective silylation, alkylation and acetalisation of the spatially different hydroxy termini is described.