Two-chain and gemini catanionic analogs of galactosylceramide were easily prepared in quantitative yields, affording high anti-HIV activities with low cytotoxicities on human cells (e.g. for gemini 4b an EC50 of 0.5 µM with a CC50 of >100 µM were obtained).
M. Blanzat, E. Perez, I. Rico-Lattes and A. Lattes, New J. Chem., 1999, 23, 1063 DOI: 10.1039/A905417K
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