SCHEDULED MAINTENANCE
A convenient one-pot synthesis of pyrimido[4,5-b]quinolines as non-classical 5-deaza antifolate inhibitors by the reaction of 6-amino-4-oxo-2-thioxotetrahydropyrimidine 1 with aromatic aldehydes and dimedone is reported.
H. A. Abdel Naby, R. A. Mekheimer, A. M. Abd-Elhameed and K. U. Sadek, J. Chem. Res. (S), 1999, 678 DOI: 10.1039/A905834F
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