Issue 8, 1999

Catalytic asymmetric reaction of lithium ester enolates with imines

Abstract

An external chiral tridentate amino diether ligand 7 catalyzed the condensation reaction of a lithium ester enolate 2 with an imine 3 to give the enantiomerically enriched β-lactam 4 in high yield.

Article information

Article type
Paper

Chem. Commun., 1999, 715-716

Catalytic asymmetric reaction of lithium ester enolates with imines

K. Tomioka, M. Ahmed Hussein, T. Kambara, H. Fujieda, S. Hayashi, Y. Nomura, M. Kanai and K. Koga, Chem. Commun., 1999, 715 DOI: 10.1039/A901424A

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