Issue 16, 1999

A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications

Abstract

The ability of the paramagnetic macromolecular complex (GdDO3ASQ)30-Orn114 to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH2 groups.

Article information

Article type
Paper

Chem. Commun., 1999, 1577-1578

A macromolecular Gd(III) complex as pH-responsive relaxometric probe for MRI applications

S. Aime, S. Geninatti Crich, M. Botta, G. Giovenzana, G. Palmisano and M. Sisti, Chem. Commun., 1999, 1577 DOI: 10.1039/A900499H

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