Self-assembly of hydrogen-bonded supramolecular strands from complementary melamine and barbiturate components with chiral selection

Abstract

Mixtures of the triamino triazines 1–6 with the complementary barbiturate 7 result in molecular recognition directed self-assembly in solution and in the solid state. The cocrystallization of enantiomerically pure 1 or 2 with 7 leads to the formation of supramolecular strands, which have been characterized by crystal structure determination. When a racemic mixture of 1 and 2 is used, chiral selection occurs within strands; two homochiral strands crystallize in the unit cell, each containing a different triazine enantiomer.