Recent claims that ‘conventional hydrogen bonds may not be necessary for high efficiency and fidelity in DNA synthesis’ and that ‘DNA polymerase can exert high fidelity even when a base pair completely lacks conventional hydrogen bonds’ are shown to be in error.
T. A. Evans and K. R. Seddon, Chem. Commun., 1997, 2023 DOI: 10.1039/A705239A
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