Issue 10, 1994

Synthesis of a novel spirocyclic lactone in a potential route to squalestatin 1

Abstract

The isomeric butenolides 1 and 2 have been converted into the spiro-lactone derivative 20via sequential ring contraction–rearrangement processes. X-Ray crystal data have been obtained on compound 12b.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1994, 1259-1261

Synthesis of a novel spirocyclic lactone in a potential route to squalestatin 1

H. Abdel-Rahman, J. P. Adams, A. L. Boyes, M. J. Kelly, R. B. Lamont, D. J. Mansfield, P. A. Procopiou, S. M. Roberts, D. H. Slee and N. S. Watson, J. Chem. Soc., Perkin Trans. 1, 1994, 1259 DOI: 10.1039/P19940001259

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